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Find information about Herceptin® (trastuzumab), a targeted therapy for HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer. Who is Herceptin for? Adjuvant Breast Cancer. Herceptin is approved for the treatment of early-stage breast cancer that is Human Epidermal growth factor Receptor 2-positive (HER2+) and has spread into the lymph nodes, or is HER2+ and has not spread into the lymph nodes. If it has not spread into the lymph nodes, the cancer needs to be estrogen receptor/progesterone receptor (ER/PR)-negative or have one high risk feature.* Herceptin can be used in several different ways: As part of a treatment course including the chemotherapy drugs doxorubicin, cyclophosphamide, and either paclitaxel or docetaxel. This treatment course is known as 'AC-TH'. With the chemotherapy drugs docetaxel and carboplatin. This treatment course is known as 'TCH'. Alone after treatment with multiple other therapies, including an anthracycline (doxorubicin)-based therapy (a type of chemotherapy). *High risk is defined as ER/PR-positive with one of the following features: tumor size >2 cm, age <35 years, or tumor grade 2 or 3. Metastatic Breast Cancer Herceptin has 2 approved uses in metastatic breast cancer: Herceptin in combination with the chemotherapy drug paclitaxel is approved for the first line treatment of Human Epidermal growth factor Receptor 2-positive (HER2+) metastatic breast cancer. Herceptin alone is approved for the treatment of HER2+ breast cancer in patients who have received one or more chemotherapy courses for metastatic disease. Gastric Cancer: Herceptin is approved, in combination with chemotherapy (cisplatin and either capecitabine or 5-fluorouracil), for the treatment of HER2+ metastatic cancer of the stomach or gastroesophageal junction (where the esophagus meets the stomach) in patients who have not received prior treatment for their metastatic disease. Important Patient Safety Information Possible Serious Side Effects With HERCEPTIN Not all people have serious side effects, but side effects with HERCEPTIN therapy are common. Although some people may have a life-threatening side effect, most do not. Your doctor will stop treatment if any serious side effects occur. HERCEPTIN is not for everyone. Be sure to contact your doctor if you are experiencing any of the following: HEART PROBLEMS These include heart problems—such as congestive heart failure or reduced heart function—with or without symptoms. The risk for and seriousness of these heart problems were highest in people who received both HERCEPTIN and a certain type of chemotherapy (anthracycline). In a study of adjuvant (early) breast cancer, one patient died of significantly weakened heart muscle. Your doctor will check for signs of heart problems before, during, and after treatment with HERCEPTIN. INFUSION REACTIONS, including: • Fever and chills • Feeling sick to your stomach (nausea) • Throwing up (vomiting) • Pain (in some cases at tumor sites) • Headache • Dizziness • Shortness of breath These signs usually happen within 24 hours after receiving HERCEPTIN. Be sure to contact your doctor if you: Are a woman who could become pregnant, or may be pregnant HERCEPTIN may result in the death of unborn baby and birth defects. Birth control should be used while receiving HERCEPTIN after your last dose of HERCEPTIN. If you are exposed to HERCEPTIN during pregnancy or within 7 months of becoming pregnant, you are encouraged to enroll in the MotHER Pregnancy Registry by contacting 1-800-690-6720 or visiting http://www.motherpregnancyregistry.com/ and report HERCEPTIN exposure to Genentech at 1-888-835-2555. Have any signs of SEVERE LUNG PROBLEMS, including • Severe shortness of breath • Fluid in or around the lungs • Weakening of the valve between the heart and the lungs • Not enough oxygen in the body • Swelling of the lungs • Scarring of the lungs Your doctor may check for signs of severe lung problems when he or she examines you. Have LOW WHITE BLOOD CELL COUNTS Low white blood cell counts can be life threatening. Low white blood cell counts were seen more often in patients receiving HERCEPTIN plus chemotherapy than in patients receiving chemotherapy alone. Your doctor may check for signs of low white blood cell counts when he or she examines you. Other Important Information Before taking HERCEPTIN, you must have a HER2 test to determine if your cancer is HER2-positive. This is because the benefit of treatment with HERCEPTIN has been shown only in patients whose tumors are HER2-positive. Side Effects Seen Most Often With HERCEPTIN Some patients receiving HERCEPTIN for breast cancer had the following side effects: • Fever • Feeling sick to your stomach (nausea) • Throwing up (vomiting) • Infusion reactions • Diarrhea • Infections • Increased cough • Headache • Feeling tired • Shortness of breath • Rash • Low white and red blood cell counts • Muscle pain Some patients receiving HERCEPTIN for metastatic stomach cancer had the following side effects: • Low white blood cell counts • Diarrhea • Feeling tired • Low red blood cell counts • Swelling of the mouth lining • Weight loss • Upper respiratory tract infections • Fever • Low platelet counts • Swelling of the mucous membranes • Swelling of the nose and throat • Change in taste You should contact your doctor immediately if you have any of the side effects listed above. You are encouraged to report side effects to Genentech and the FDA. You may report side effects to the FDA at 1–800–FDA–1088 or http://www.fda.gov/medwatch. You may also report side effects to Genentech at 1–888–835–2555. Please see additional select Important Safety Information throughout, and the full Prescribing Information, including Boxed WARNINGS.
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Aspect | Summary |
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Website load speed: | 1.7826s this is quite good! |
Number of (outgoing) links: | 40 |
HTML size: | 37.4 kilobytes Good |
Herceptin.com HTTP headers
HTTP/1.0 301 Moved Permanently
Location: http://www.herceptin.com/
Server: BigIP
Connection: Keep-Alive
Content-Length: 0
IP address in detail
The following domains are, too, hosted on 72.34.128.114:
Keywords
A total of 6 keywords are used by the website
- her2
- trastuzumab
- herceptin
- breast cancer treatment
- her2 positive breast cancer
- her2 positive gastric cancer
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Global Alexa rating
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Herceptin.com
Lowest rating: | spotted 3,730 days ago |
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Current rating: | spotted 3,728 days ago |
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Best rating: | spotted 3,728 days ago |
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It seems herceptin.com has only been registered once and was never abandoned or has never expired.
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Herceptin.com
Current rating: | spotted 3,733 days ago |
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Worst rating: | spotted 3,809 days ago |
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Best rating: | spotted 3,755 days ago |
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